Cannabis-based infusions have been around since as early as 1450 BC. The Biblical book of Exodus refers to anointing oil made from “…kaneh-bosem, a substance we identify as cannabis today. So, to say that the cannabis plant has been an important part of the human healing culture would be an understatement.
More research is needed to understand how THC and CBD provide wellness benefits. However, have you ever wondered about the differences between hemp seed oil and cannabis extractions? Let’s get into it.
What is Cannabidiol (CBD)?

While THC gets most of the attention, the other major cannabinoid found in agricultural hemp (cannabidiol) is a wellness rockstar. Because cannabidiol (CBD) has minimal psychoactive properties and you cannot “get high” on CBD, it has been extensively studied worldwide for its medicinal properties.
CBD, short for cannabidiol, is a compound found in both marijuana and hemp plants. However, the source of CBD can vary depending on where it comes from. While CBD can be derived from marijuana plants, it’s more commonly extracted from hemp plants.
Here’s the difference: Marijuana and hemp are both types of cannabis plants, but they have distinct characteristics. Marijuana is known for its high THC content, which is the psychoactive compound that makes you feel “high.” Hemp, on the other hand, contains very low levels of THC but is rich in CBD.
When CBD is extracted from marijuana plants, it may contain higher levels of THC, which could potentially cause psychoactive effects. However, CBD extracted from hemp plants typically contains negligible amounts of THC, making it non-intoxicating and legal in many places.
So, while CBD can be made from marijuana plant material, it’s more commonly sourced from hemp plants, which provide a CBD-rich extract without the high.
Is CBD Made From Marijuana Plant Material?
CBD, short for cannabidiol, is a compound found in both marijuana and hemp plants. However, the source of CBD can vary depending on where it comes from. While CBD can be derived from marijuana plants, it’s more commonly extracted from hemp plants.
Here’s the difference: Marijuana and hemp are both types of cannabis plants, but they have distinct characteristics. Marijuana is known for its high THC content, which is the psychoactive compound that makes you feel “high.” Hemp, on the other hand, contains very low levels of THC but is rich in CBD.
When CBD is extracted from marijuana plants, it may contain higher levels of THC, which could potentially cause psychoactive effects. However, CBD extracted from hemp plants typically contains negligible amounts of THC, making it non-intoxicating and legal in many places.
So, while CBD can absolutely be made from marijuana plant material, it’s more commonly sourced from hemp plants, which provide a CBD-rich extract without the high. All CBD products must have 0.30% THC or less, or they are federally illegal. Using agricultural hemp instead of cannabis plants makes it easier to ensure the required lower level of THC for legal compliance.
Potential Health Benefits of Consuming CBD Daily

Incorporating CBD into your daily routine can offer a variety of potential health benefits. Many people find that CBD helps them manage stress more effectively, promoting relaxation without the intoxicating effects of THC. Additionally, CBD may improve sleep quality, making it easier to fall asleep and stay asleep throughout the night.
Beyond stress and sleep, CBD has also been studied for its potential to alleviate pain, whether it’s chronic discomfort or post-workout soreness. Moreover, CBD may contribute to overall mood enhancement, with research suggesting it could have antidepressant and anxiety-reducing effects.
Relief from Everyday Stress
In today’s fast-paced society, stress seems to be an inevitable part of life for many. Fortunately, CBD, or cannabidiol, offers a natural remedy that can help alleviate the burdens of daily stress. But how does it work?
CBD interacts with the body’s endocannabinoid system (ECS), which is a complex network of receptors and neurotransmitters that helps regulate various physiological processes, including mood, stress response, appetite, and more. When CBD is consumed, it indirectly influences the ECS by enhancing the activity of endocannabinoids, the body’s natural neurotransmitters.
Specifically, CBD inhibits the reuptake of anandamide, a neurotransmitter often referred to as the “bliss molecule” due to its role in promoting feelings of happiness and well-being. By prolonging the presence of anandamide in the brain, CBD may help combat stress and promote a sense of relaxation without inducing the psychoactive effects commonly associated with THC.
Additionally, CBD interacts with serotonin receptors, which play a crucial role in regulating mood and anxiety levels. By modulating serotonin signaling, CBD may exert anxiolytic (anxiety-reducing) effects, further contributing to its stress-relieving properties.
Furthermore, CBD’s ability to promote relaxation extends beyond its interactions with neurotransmitters. Research suggests that CBD may also influence the activity of the hypothalamic-pituitary-adrenal (HPA) axis, a key component of the body’s stress response system. By modulating HPA axis function, CBD can help regulate cortisol levels, the primary stress hormone, thereby mitigating the physiological effects of stress on the body.
Better Sleep Quality
A restful night’s sleep is essential for overall health and well-being, yet many individuals struggle with insomnia and sleep disturbances. If you find yourself tossing and turning at night, CBD may offer a natural solution to help you achieve better sleep quality.
CBD’s potential to improve sleep is attributed to its interactions with the endocannabinoid system (ECS), a regulatory network responsible for maintaining balance throughout the body. By influencing the activity of cannabinoid receptors within the ECS, CBD can modulate various physiological processes, including sleep-wake cycles.
One way in which CBD promotes better sleep quality is by addressing underlying factors that contribute to sleep disturbances, such as anxiety and stress. CBD has been shown to possess anxiolytic (anxiety-reducing) properties, helping to calm the mind and promote relaxation before bedtime. By alleviating feelings of anxiety and promoting a sense of calm, CBD can create an optimal environment for falling asleep and staying asleep throughout the night.
Additionally, CBD may enhance sleep by regulating circadian rhythms, the internal biological clock that governs the sleep-wake cycle. Research suggests that CBD interacts with receptors involved in circadian rhythm regulation, thereby promoting a more consistent sleep-wake pattern and reducing the likelihood of nighttime awakenings.
Furthermore, CBD’s ability to alleviate pain and discomfort can contribute to better sleep quality. Chronic pain conditions, such as arthritis or fibromyalgia, can disrupt sleep by causing discomfort and restlessness. CBD’s analgesic (pain-relieving) properties can help alleviate pain symptoms, allowing for more restful sleep without the interruption of discomfort.
By addressing both physical and psychological factors that influence sleep quality, CBD offers a comprehensive approach to improving overall sleep health. Whether you struggle with insomnia, nighttime anxiety, or chronic pain, incorporating CBD into your nightly routine can help you achieve the restorative sleep you need to wake up feeling refreshed and rejuvenated.
Pain Management
Chronic pain affects millions of individuals worldwide, impacting their quality of life and overall well-being. If you’re seeking relief from persistent pain, CBD may offer a natural alternative that can help alleviate discomfort and improve your daily functioning.
CBD’s potential to manage pain is attributed to its interactions with the endocannabinoid system (ECS), a complex network of receptors and neurotransmitters that plays a key role in regulating pain perception. Within the ECS, CBD modulates the activity of cannabinoid receptors, such as CB1 and CB2, which are involved in pain signaling pathways.
One way CBD alleviates pain is by inhibiting the transmission of pain signals to the brain. When injured or inflamed, tissues release chemical signals that activate pain receptors, triggering sensations of discomfort. CBD interacts with these pain receptors, reducing their sensitivity to pain stimuli and dampening the transmission of pain signals to the central nervous system.
Additionally, CBD possesses anti-inflammatory properties that can help reduce inflammation and swelling associated with various types of pain, including arthritis, neuropathy, and muscle soreness. By mitigating inflammation, CBD addresses the underlying cause of pain and provides symptomatic relief, allowing individuals to experience greater comfort and mobility.
Furthermore, CBD’s analgesic (pain-relieving) effects extend beyond its interactions with the endocannabinoid system. Research suggests that CBD influences the activity of neurotransmitters involved in pain modulation, such as serotonin and glutamate, thereby enhancing its pain-relieving properties.
Whether you’re dealing with chronic pain conditions or acute discomfort from injuries or overexertion, CBD offers a natural alternative that can help manage pain and improve your quality of life. By targeting pain pathways, reducing inflammation, and modulating neurotransmitter activity, CBD provides effective relief without the adverse side effects associated with conventional pain medications.
Mood Enhancement
Maintaining a positive mood and emotional well-being is essential for overall happiness and quality of life. If you’re struggling with mood disorders such as depression or anxiety, CBD may offer a natural remedy that can help uplift your spirits and promote emotional balance.
CBD’s potential to enhance mood is attributed to its interactions with the endocannabinoid system (ECS), a complex network of receptors and neurotransmitters that plays a key role in regulating mood, stress response, and emotional processing. Within the ECS, CBD modulates the activity of cannabinoid receptors, such as CB1 and CB2, which regulate mood.
One way in which CBD exerts its mood-enhancing effects is by increasing the availability of serotonin, a neurotransmitter often referred to as the “feel-good” molecule due to its role in promoting happiness and well-being. CBD inhibits the reuptake of serotonin, allowing it to remain active in the brain for longer periods and enhancing its mood-stabilizing effects.
Additionally, CBD interacts with other neurotransmitter systems implicated in mood regulation, such as the endocannabinoid, dopamine, and glutamate systems. By modulating the activity of these neurotransmitters, CBD can help regulate emotional responses, reduce feelings of anxiety and depression, and promote a more positive outlook on life.
Furthermore, CBD’s anxiolytic (anxiety-reducing) properties can contribute to its mood-enhancing effects. Research suggests that CBD can help alleviate symptoms of anxiety disorders, such as generalized anxiety disorder (GAD) and social anxiety disorder (SAD), by promoting relaxation and reducing stress levels.
Cannabidiol May Help Diabetic Glucose Management
Emerging research suggests that cannabidiol (CBD) may offer potential benefits for diabetic glucose management. CBD interacts with the body’s endocannabinoid system, regulating various physiological processes, including metabolism and insulin sensitivity.
Studies have shown that CBD may help improve insulin function and glucose tolerance, potentially leading to more stable blood sugar levels in individuals with diabetes. Additionally, CBD has anti-inflammatory properties that could alleviate complications associated with diabetes, such as neuropathy and cardiovascular issues.
While more research is needed to fully understand the mechanisms underlying CBD’s effects on glucose management, these preliminary findings highlight its potential as a natural supplement for individuals with diabetes seeking alternative methods for controlling their blood sugar levels.
As always, it’s important for individuals with diabetes to consult with their healthcare provider before incorporating CBD into their treatment regimen. For individuals who struggle with symptom management, cannabis healthcare providers often recommend taking a daily full-spectrum CBD oil or capsule. You can take CBD when you use medical cannabis on a regular basis.
Do Your Research Before You Buy CBD Products
Cannabidiol, or CBD, can be formulated in a variety of wellness products, from CBD topicals that can help with wound care, dry skin, and local pain relief to dietary supplements in the form of tinctures (sublingual uptake), edibles (gummies or losengers), capsules, and tablets.
All CBD products are not created equal. In fact, the FDA has sent hundreds of warning letters and taken legal action against companies that make CBD supplements. The problem is that currently, cannabidiol products are not regularly inspected by the FDA; often, counterfeit products are found because of consumer complaints.
If you have tried CBD before and didn’t notice any benefits, it is important to look at the quality of the product you tried. Never purchase CBD in oil form or a cannabidiol edible that does not have a Certificate of Analysis (COA).
Reputable brands provide information that is verified by independent or third-party batch testing. That information includes a disclosure of the concentration of cannabidiol, other additives such as natural extracts and terpenes, and more. You want to make sure that the product you are purchasing has a sufficient concentration of CBD to be effective and check that there are no contaminants, such as heavy metals or pesticides.
It may be hard to believe, but millions of CBD products are imported every year from countries that do not have the same safety standards for consumer goods. A quality CBD product will be sourced from agricultural hemp, and a COA will be provided to assure you that you are consuming a safe supplement.
What is Tetrahydrocannabinol (THC)?

Tetrahydrocannabinol, commonly known as THC, is a natural compound found in cannabis plants. It’s the chemical responsible for the psychoactive effects or the “high” associated with marijuana use. THC interacts with receptors in the brain and body, known as cannabinoid receptors, to produce its effects.
When THC is consumed, whether by smoking, vaping, or ingesting cannabis products, it binds to cannabinoid receptors, particularly in areas of the brain responsible for pleasure, memory, thinking, coordination, and perception of time. This interaction leads to the euphoric and psychoactive sensations that users experience.
THC levels can vary depending on the strain of cannabis and how it’s cultivated and processed. In recent years, there has been a growing interest in strains with higher levels of THC for recreational purposes, as well as strains with lower levels for medicinal use, where the focus is more on the potential therapeutic benefits of other cannabinoids like CBD, which doesn’t produce the same intoxicating effects as THC.
It’s important to note that while THC can induce feelings of relaxation and euphoria, it also has potential side effects, including impaired coordination, memory loss, increased heart rate, and anxiety or paranoia, especially in high doses. As such, understanding THC and its effects is crucial for individuals considering its use for recreational or medicinal purposes.
How Can THC Help Patients With Chronic Symptoms?
One of the primary ways THC helps patients is by providing pain relief. THC activates cannabinoid receptors in the brain and body, which can help alleviate discomfort associated with conditions like arthritis, multiple sclerosis, or neuropathy. Additionally, THC’s anti-inflammatory properties may further contribute to its pain-relieving effects.
THC can also help patients manage nausea and stimulate appetite. For individuals undergoing chemotherapy or dealing with conditions like HIV/AIDS, which can cause nausea and appetite loss, THC may offer relief by reducing feelings of queasiness and increasing the desire to eat.
Furthermore, THC has been studied for its potential to reduce muscle spasms and stiffness in conditions such as multiple sclerosis and Parkinson’s disease. By interacting with cannabinoid receptors in the central nervous system, THC may help relax muscles and improve mobility for patients experiencing muscle-related symptoms.
Overall, THC holds promise as a therapeutic option for patients with chronic symptoms, offering a natural alternative to traditional medications with potentially fewer side effects. However, it’s essential for patients to work with healthcare professionals to determine the most appropriate dosage and administration method for their specific needs.
Why Is Hemp and Cannabis Extracted Into an Oil Form?
Hemp and cannabis are often extracted into oil form because they allow for easy consumption and absorption of the beneficial compounds found in these plants. Oil extraction methods, such as CO2 extraction or ethanol extraction, effectively capture the cannabinoids, terpenes, and other phytochemicals present in hemp and cannabis plants, creating a concentrated and potent oil.
Additionally, oil-based extracts offer versatility in terms of consumption. Whether it’s through oral ingestion, sublingual administration, or incorporation into food and beverages, oils provide a convenient and customizable way to consume cannabinoids like CBD and THC. Moreover, oil-based formulations ensure efficient absorption in the body, as cannabinoids are lipid-soluble compounds that are readily absorbed by fat cells, allowing for optimal bioavailability and therapeutic effects.
What Are The Most Common CBD and THC Extraction Processes?
Natural organic oils present in agricultural hemp and cannabis plants must undergo an extraction process to derive the oils that are manufactured into consumer products. Almost every part of the hemp plant is used, and hemp oil is also widely used in skin and hair care products.
There are many different types of extraction methods used for both THC and cannabidiol (CBD):
Solvent Extraction
Solvent extraction is a popular method for extracting CBD and THC from cannabis and hemp plants. This process involves using solvents like ethanol, butane, or CO2 to dissolve the desired compounds from the plant material. The solvent is then evaporated, leaving behind a concentrated extract rich in cannabinoids and terpenes.
While effective, solvent extraction requires careful handling to ensure the removal of residual solvents, which can be harmful if ingested. Additionally, the choice of solvent can impact the final quality of the extract, with CO2 extraction often preferred for its safety and purity.
CO2 Extraction Process
CO2 extraction, also known as supercritical fluid extraction, utilizes carbon dioxide (CO2) in a controlled environment to extract cannabinoids and other compounds from plant material. CO2 is pressurized to become a supercritical fluid, capable of acting as both a gas and a liquid to dissolve and extract target compounds efficiently.
The CO2 method offers several advantages, including high selectivity, as CO2 can be fine-tuned to target specific cannabinoids, and minimal post-extraction processing, resulting in a clean and pure extract free from solvent residues.
Hydrocarbon Extraction Method
Hydrocarbon extraction involves using hydrocarbon solvents such as butane, propane, or hexane to extract cannabinoids from cannabis and hemp plants. This method is known for its efficiency in extracting a wide range of compounds, including cannabinoids, terpenes, and flavonoids.
However, compared to other methods, hydrocarbon extraction carries a higher risk of residual solvent contamination, requiring thorough purification steps to ensure product safety. Proper ventilation and safety protocols are essential when utilizing hydrocarbon extraction due to the flammable nature of the solvents involved.
Ethanol Extraction
Ethanol extraction is a traditional method for extracting cannabinoids from cannabis and hemp plants using food-grade ethanol as a solvent. The plant material is soaked in ethanol to dissolve the desired compounds, which are then separated from the solvent through filtration or evaporation.
Ethanol extraction is relatively simple and cost-effective, making it a popular choice for small-scale operations. However, it can also extract undesirable compounds like chlorophyll, requiring additional refinements to produce a high-quality extract. Ethanol extraction is considered safe for consumption when performed correctly, but residual solvent testing is recommended to ensure that the final products do not contain harmful chemicals.
Lipid Extraction Process
Lipid extractions lipid infusion, or lipid-based extraction, involves using fats or oils to extract cannabinoids and terpenes from cannabis and hemp plants. This method harnesses the affinity of cannabinoids for lipid molecules, allowing for efficient extraction without the need for harsh solvents.
Plant material is soaked or steeped in a lipid-rich solvent, such as coconut oil or olive oil, to extract the desired compounds, which are then strained and separated from the plant material. Lipid extraction is favored for its simplicity and safety, as it avoids the use of potentially harmful solvents. However, it may result in lower cannabinoid concentrations compared to other extraction methods, requiring larger volumes of oil for comparable potency.
Which Extraction Process is Better or Healthier?
Lipid extraction, also known as lipid infusion or lipid-based extraction, typically carries the lowest risk of adverse effects or chemical exposure for humans. Unlike solvent-based extraction methods such as hydrocarbon or ethanol extraction, which involve the use of potentially harmful solvents, lipid extraction utilizes fats or oils as the extracting agent. This method harnesses the natural affinity of cannabinoids for lipid molecules, allowing for efficient extraction without the need for harsh chemicals.
Lipid extraction is considered safe for human consumption, as it avoids the risk of residual solvent contamination associated with solvent-based methods. Additionally, lipid extraction is relatively simple and straightforward, making it an attractive option for producing high-quality CBD and THC extracts with minimal risk to consumer health.
What are the differences between Hemp Seed Oil, Hemp Oil, and Marijuana Oil?

Hemp seed oil is made from the seeds of the hemp plant. It is a good carrier oil—it can be used to dilute essential oils for massages, aromatherapy, or skin care applications. Although it contains no CBD, it is rich in antioxidants, omega fatty acids, and amino acids.
Cannabidiol is extracted from the parts of the hemp plant high in CBD and comes from plants containing less than 0.3% THC by dry weight. Much like other edible oils, there are different grades and types of thc and their benefits.
- Broad Spectrum CBD Oil can best be described as full-spectrum CBD oil with all traces of THC removed.
- Full Spectrum CBD Oil comes from the full plant and contains CBD as well as other cannabinoids, terpenes, and flavonoids. It can also contain trace amounts of THC, which may show up on a drug test.
- Isolates only contain pure CBD oil. During the extraction process, other cannabinoids, including THC, terpenes, and flavonoids, are removed.
Marijuana Oil is extracted from marijuana plants containing more than 0.3% THC. Depending on the process used, it may include part or all of the beneficial components of the plant.
- Rick Simpson Oil is made using food-grade alcohol. Because the alcohol must be removed at a certain time and temperature, the resulting product has already been decarboxylated or activated, so it can be taken orally or sublingually instead of needing to be smoked or vaporized.
- Butane Honey Oil/BHO uses liquid butane as a solvent. The butane is later removed using one of a number of techniques. BHO is resin-like, thick, and sticky. It is generally high in cannabinoids and THC. It can be dabbed or used in a portable vaporizer.
- Distillates are the result of using heat to vaporize cannabinoids, stripping everything else away. This produces a highly concentrated, clean, solvent-free liquid. Unfortunately, the heat required for distillation destroys terpenes; if the finished product is to include terpenes, they must be added back in after the process is complete. Without the reintroduction of terpenes, distillates are odorless and tasteless.
Cannabidiol (CBD) and cannabis show promise in treating a number of health conditions. Their benefits are widespread, whether used on the skin, taken orally, or made into edibles. Licensed dispensaries are the safest place to purchase medicinal cannabis oil, and they will provide certificate of analysis information for all products they sell.
When choosing a CBD supplement, stick to products made in the United States and sourced from organic agricultural hemp. Don’t forget to check and review the certificate of analysis (COA) to make sure you are getting a clinical-grade CBD supplement (with no dangerous chemicals or additives). Remember to also check for THC and CBD ratios in any products you are using for medicinal purposes.

Dr. Glider is a board certified Internal Medicine Specialist. He received his Florida Medical Marijuana Physicians Certification in 2017 and was one of the first recommending physicians with DocMJ. In addition to medical marijuana recommendations, Dr. Glider continues to practice Internal and Geriatric Medicine in private practice. Additionally, he serves as Medical Director for a home health company, supervising and educating staff, as well as supervising an advanced Registered Nurse Practitioners for a transitional care program.
Dr. Glider graduated from the College of Osteopathic Medicine & Surgery in Des Moines, IA and completed his residency at Saddlebrook General Hospital in Saddlebrook, NJ. He has received several honors and awards throughout his professional career, including a City of Des Moines Merit Award and a Chamber of Commerce Award (Port St. Lucie, FL). Dr. Glider is an experienced and caring physician who is loved and respected by his peers and his patients.
